Himalaya Serpina. Serpina is the world's first natural anti-hypertensive drug. Serpina causes depletion of peripheral storage catecholamine (norepinephrine), which causes a reduction in blood pressure. Serpina decreases the adrenergic tone, control anxiety and is beneficial in the treatment of anxiety disorders. Restores normal blood pressure in hypertensives. Recommendations : Mild to moderate degree of hypertension. Ingredients : Sarpagandha (Rauwolfia serpentina) 4mg. Key ingredient: Rauwolfia (Sarpagandha) is a pungent smelling herb, which is a potent anti-hypertensive. Its Sanskrit name, Sarpagandha, literally translates to 'smells like a serpent'. Reserpine, an active compound found in Rauwolfia, renders the herb its antihypertensive property. Its anti-hypertensive activity is attributed to a decrease in peripheral resistance and the resulting decrease in cardiac output.